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E – SDF (Silver Diamine Flouride 3.25ml)

Brand: E-SDF

High caries-risk patients with anterior or posterior activecavitated lesions, havioral or medical management challenges, Patients with multiple cavitated caries lesions that may notall be treated in one visit, Difficult to treat cavitated dental caries lesions, Patients without access to or with difficulty accessing dental care, Active cavitated caries lesions with no clinical signs of pulp involvement.

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Description

It is a safe, painless alternative to traditional cavity drilling procedure

Ideally e- SDFhelps in Preventing and arresting dental caries & immediate relief from dentinal hypersensitivity

Research on use of Silver Diamine Fluoridesaysexposure toone drop ofSDF orally would result in less fluoride ion contentthan ispresent in a 0.25 mLtopical treatment of fluoride varnish. The exact amount of silver and fluoride present in one drop ofSDF is determined by the specific gravity of the liquid and thedropper used.

Themain disadvantage of SDFis its esthetic result (i.e., permanently blackens enamel and dentinal caries lesions andcreates a temporary henna-appearing tattoo if allowed to comein contact with skin).Skin pigmentationistemporarysincethe silver does not penetrate the dermis

Practical Applications in the following cases:

  • High caries-risk patients with anterior or posterior activecavitated lesions
  • havioral or medical management challenges
  • Patients with multiple cavitated caries lesions that may notall be treated in one visit
  • Difficult to treat cavitated dental caries lesions
  • Patients without access to or with difficulty accessing dental care
  • Active cavitated caries lesions with no clinical signs of pulp involvement.
  • Key Specifications

    COMPOSITION:

    • Silver diamine fluoride contains approximately 24-28 % (weight/volume) silver and 5-6 % (weight/volume)
    • Packaging

      • 1 x E-SDF Bottle
      • Direction to Use

        Carious dentin excavation prior to SDF application is not necessary. Caries dentin excavation may reduce proportion of arrested caries lesions that become black, and may be considered for esthetic purposes.

        Functional indicator of effectiveness (i.e., caries arrest) is when staining on dentinal carious surfaces is visible

        The following steps may vary depending on differing prac-tices, settings, and patients:

        • Remove gross debris from cavitation to allow better SDFcontact with denatured dentin
        • Minimize contact with gingiva and mucous membranes toavoid potential pigmentation or irritation; consider apply-ing cocoa butter or use cotton rolls to protect surroundinggingival tissues, with care to not inadvertently coat thesurfaces of the carious lesion.
        • Dry with a gentle flow of compressed air (or use cotton >rolls/gauze to dry) affected tooth surfaces
        • Bend micro sponge brush, dip and dab on the side of the dappen dish to remove excess liquid before application;24 apply SDF directly to only the affected tooth surface
        • Dry with a gentle flow of compressed air for at least one minute
        • Remove excess SDF with gauze, cotton roll, or cotton pelletto minimize systemic absorption
        • Continue to isolate sitefor up to three minutes when possible

        Practical recommendation:No need for surgical intervention(e.g., dentin excavation). SDF application is minimally invasiveand easy for the patient and the practitioner. It may be desirablefor the caries lesion to be free of gross debris for SDF to havemaximum contact with the affected dentin surface

        Application time

        An application time of one minute, drying with a gentle flowof compressed air, is recommended. Clinical studies that reportapplication times range from 10 seconds to three minutes. Acurrent review states that application time in clinical studiesdoes not correlate to outcome.24More studies are needed toconfirm an ideal protocol

        POST OPERATIVE INSTRUCTIONS:

        No postoperative limitations are listed by the manufacturer.Eating and drinking immediately following application isacceptable. Patients may brush with fluoridated toothpaste asper regular routine following SDF application.Several SDF clinical trials recommended no eating or drink-ing for 30 minutes one hour.13,31,32As patients are used tothese recommendations for in-office topical fluoride applications,the recommendation may not be unreasonable to patients, andit may allow for better arrest results. More clinical studies areneeded to establish best practices

        Application frequency:

        The effectiveness of one-time SDF application in arresting dentalcaries lesions ranges from 47 percent to 90 percent, dependingon the lesion size and the location of the tooth and the lesion.One study showed that anterior teeth had higher rates ofcaries lesion arrest than posterior teeth

        The effectiveness ofcaries lesion arrest, however, decreases over time. After a singleapplication of 38 percent SDF, 50 percent of the arrested sur-faces at six months had reverted to active lesions at 24 months.

        Reapplication may be necessary to sustain arrest.Annualapplication of SDF is more effective in arresting caries lesionsthan application of five percent sodium fluoride varnish fourtimes per year.

        Increasing frequency of application can increasecaries arrest rate. Biannual application of SDF increased the rateof caries lesion arrest compared to annual applicationStudiesthat had three times per year applications showed higher arrestrates.Frequency of application after baseline has beensuggested at three month follow up, and then semiannual recallvisits over two years

        One option is to place SDF on activelesions in conjunction with fluoride varnish (FV) on the rest ofthe dentition, or alternate SDF on caries lesions and FV on therest of the dentition at three months interval to achieve arrestand prevention in high risk individuals.Another study recom-mends one month post operative evaluation of treated lesionswith optional reapplication as required to achieve arrest of alltargeted lesions.Individuals with high plaque index and lesionswith plaque present display lower rates of arrest. Addressingother risk factors like presence of plaque may increase the rate ofsuccessful treatment outcomes.

        FAQs

        What is e-SDF?

        • E-SDF is a silver diamine fluoridethat helps in Preventing and arresting dental caries & immediate relief from dentinal hypersensitivity

        In what all cases a dentist can use e-SDF?

        • High caries-risk patients with anterior or posterior active cavitated lesions
        • havioral or medical management challenges
        • Patients with multiple cavitated caries lesions that may not all be treated in one visit
        • Difficult to treat cavitated dental caries lesions
        • Patients without access to or with difficulty accessing dental care
        • Active cavitated caries lesions with no clinical signs of pulp involvement.

        What should be the application time?

        • Ideal application time is 1 minute

        How many times i can use it in a patient ? Does it have any harmful effect in oral cavity?

        • Studies have suggested the use of e-SDF according to the patients with high to low caries risk:

        In patients with high caries risk:

        • e-SDF can be applied from 3-4 times annually with atleast a gap of 3-4 months

        In patients with moderate to low caries risk:

        • e-SDF can be applied from 1-2 times annually with atleast a gap of 5-6 months

        Yes, it does have few side effects:

        Themain disadvantage of SDFis its esthetic result (i.e., permanently blackens enamel and dentinal caries lesions and creates a temporary henna-appearing tattoo if allowed to come in contact with skin).Skin pigmentationistemporarysince the silver does not penetrate the dermis

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